IMIB - Institute for Molecular Infection Biology

2012

Corcoran C, Podkaminski D, Papenfort K, Urban JH, Hinton JC, Vogel J (2012)
Superfolder GFP reporters validate diverse new mRNA targets of the classic porin regulator, MicF RNA
Molecular Microbiology in press

Argaman L, Elgrably-Weiss M, Hershko T, Vogel J, Altuvia S (2012)
RelA protein stimulates the activity of RyhB small RNA by acting on Hfq
PNAS in press

Papenfort K, Podkaminski D, Hinton JC, Vogel J (2012)
The ancestral SgrS RNA discriminates horizontally acquired Salmonella mRNAs through a single G-U wobble pair
PNAS in press

Tischer M, Pradel G, Ohlsen K, Holzgrabe U (2012)
Quaternary ammonium salts and their antimicrobial potential: targets or
nonspecific interactions?
ChemMedChem 2012 Jan 2;7(1):22-31

Ziebuhr W, Flückiger U (2012)
Coagulase-negative Staphylococci
p443-462 In C G Mayhall (ed)Hospital Epidemiology and Infection ControlLippincott Williams & Wilkins, Philadelphia, PA

Weyler M, Morschhäuser J (2012)
Tetracycline-Inducible Gene Expression in Candida albicans
Methods Mol Biol 2012;845:201-10

Sasse C, Morschhäuser J (2012)
Gene Deletion in Candida albicans Wild-Type Strains Using the SAT1-Flipping Strategy
Methods Mol Biol 2012;845:3-17

Depke M, Burian M, Schäfer T, Bröker BM, Ohlsen K, Völker U (2012)
The alternative sigma factor B modulates virulence gene expression in a murine Staphylococcus aureus infection model but does not influence kidney gene expression pattern of the host
Int J Med Microbiol 302(1):33-9

Donat S, Hasenberg M, Schäfer T, Ohlsen K, Gunzer M, Einsele H, Löffler J, Beilhack A, Krappmann S (2012)
Surface display of Gaussia princeps luciferase allows sensitive fungal pathogen detection during cutaneous aspergillosis
Virulence 3(1) [Epub ahead of print]

Zhelyazkova P, Sharma CM, Förstner KU, Liere K, Vogel J, Börner T (2012)
The primary transcriptome of barley chloroplasts: numerous non-coding RNAs and the dominating role of the plastid-encoded RNA polymerase
Plant Cell 24(1):123-36

Ramachandran VK, Shearer N, Jacob JJ, Sharma CM, Thompson A (2012)
The architecture and ppGpp-dependent expression of the primary transcriptome of Salmonella Typhimurium during invasion gene expression
BMC Genomics 13:25

Wilms I, Overlöper A, Nowrousian M, Sharma CM, Narberhaus F (2012)
SF RNA Virulence: Deep sequencing uncovers numerous small RNAs on all four replicons of the plant pathogen Agrobacterium tumefaciens
RNA Biol 9(4) [Epub ahead of print]

Madhugiri R, Pessi G, Voss B, Hahn J, Sharma CM, Reinhardt R, Vogel J, Hess WR, Fischer HM, Evguenieva-Hackenberg E (2012)
Small RNAs of the Bradyrhizobium/Rhodopseudomonas lineage and their analysis
RNA Biol 1;9(1)

Pernitzsch SR&  Sharma, CM (2012)
Transcriptome complexity and riboregulation in the human pathogen Helicobacter pylori
Frontiers in Cellular and Infection
Microbiology, in press

Schneider J, Yepes A, Garcia-Betancur JC, Westedt I, Mielich B, López D (2012)
Streptomycin-induced expression in Bacillus subtilis of YtnP, a lactonase-homologous protein that inhibits development and streptomycin production in Streptomyces griseus
Appl Environ Microbiol 78(2): 599-603

García-Betancur JC, Yepes A, Schneider J, López D (2012)
Single-cell analysis of Bacillus subtilis biofilms using fluorescence microscopy and flow cytometry
J Vis Exp 60: 1-8

2011 

Fröhlich KS, Papenfort K, Berger AA, Vogel J (2011)
A conserved RpoS-dependent small RNA controls the synthesis of major porin OmpD
Nucleic Acids Res Dec 17

Solyakov L, Halbert J, Alam MM, Semblat JP, Dorin-Semblat D, Reininger L, Bottrill AR, Mistry S, Abdi A, Fennell C, Holland Z, Demarta C, Bouza Y, Sicard A, Nivez MP, Eschenlauer S, Lama T, Thomas DC, Sharma P, Agarwal S, Kern S, Pradel G, Graciotti M, Tobin AB, Doerig C (2011)
Global kinomic and phospho-proteomic analyses of the human malaria parasite Plasmodium falciparum
Nat Commun Nov 29;2:565

Belair C, Baud J, Chabas S, Sharma CM, Vogel J, Staedel C, Darfeuille F (2011)
Helicobacter pylori interferes with an embryonic stem cell micro RNA cluster to block cell cycle progression
Silence 25;2(1):7

Böhm A, Papenfort K, Lopez D, Vogel J (2011)
Microbes at their best: first Mol Micro Meeting Würzburg
Mol Microbiol 82(4):797-806

Albrecht M, Sharma CM, Dittrich MT, Muller T, Reinhardt R, Vogel J, Rudel T (2011)
The transcriptional landscape of Chlamydia pneumonia
Genome Biol 11;12(10):R98

Schmidtke C, Findeiß S, Sharma CM, Kuhfuß J, Hoffmann S, Vogel J, Stadler PF, Bonas U (2011)
Genome-wide transcriptome analysis of the plant pathogen Xanthomonas identifies sRNAs with putative virulence functions
NAR, Nov 12

Beckmann BM, Burenina OY, Hoch PG, Kubareva EA, Sharma CM, Hartmann RK1 (2011)
In vivo and in vitro analysis of 6S RNA-templated short transcripts in Bacillus subtilis
RNA Biology 8(5)

Depke M, Burian M, Schäfer T, Bröker BM, Ohlsen K, Völker U (2011)
The alternative sigma factor B modulates virulence gene expression in amurine Staphylococcus aureus infection model but does not influence kidney gene expression pattern of the host
Int J Med Microbiol  21 Sept

Desai PR, Thakur A, Ganguli D, Paul S, Morschhauser J, Bachhawat AK (2011)
Glutathione utilization by Candida albicans requires a functional DUG pathway and OPT7, an unusual member of the oligopeptide transporter family
J Biol Chem  12 [Epub ahead of print]

Sasse C, Schillig R, Dierolf F, Weyler M, Schneider S, Mogavero S, Rogers PD, Morschhäuser J (2011)
The transcription factor Ndt80 does not contribute to Mrr1-, Tac1-, and Upc2-mediated fluconazole resistance in Candida albicans
PLoS One 6(9):e25623. Epub  Sep 27

Hartmann T, Cairns TC, Olbermann P, Morschhäuser J, Bignell EM, Krappmann S (2011)
Oligopeptide transport and regulation of extracellular proteolysis are required for growth of Aspergillus fumigatus on complex substrates but not for virulence
Mol Microbiol  82(4):917-35

Röhrich CR, Ngwa CJ, Wiesner J, Schmidtberg H, Degenkolb T, Kollewe C, Fischer R, Pradel G, Vilcinskas A (2011)
Harmonine, a defence compound from the harlequin ladybird, inhibits
mycobacterial growth and demonstrates multi-stage antimalarial activity
Biol Lett 21 [Epub ahead of print]

Humeida H, Pradel G, Stich A, Krawinkel MB (2011)
The effect of glucose and insulin on in vitro proliferation of Plasmodium falciparum
J Diabetol  3, 6
Gogol EB, Rhodius VA, Papenfort K, Vogel J#, Gross CA# (2011)
Small RNAs endow a transcriptional activator with essential repressor functions for single-tier control of a global stress regulon
PNAS 108(31):12875-80

Vogel J, Luisi B (2011)
Hfq and its constellation of RNA
Nature Reviews Microbiology  9(8):578-89

Corcoran C, Papenfort K, Vogel J (2011)
Hfq-associated regulatory small RNAs
In: Regulatory RNAs in Prokaryotes, Eds. A. Marchfelder, W.R. Hess, Springer Germany, in press

Podkaminski D, Bouvier M, Vogel J (2011)
Identification and characterization of small noncoding RNAs in bacteria
In: Handbook of RNA Biochemistry (eds. Hartmann RK, Bindereif A, Schön A, Westhof E), Wiley-VCH, in press

Brakhage AA, Gross U, Morschhäuser J (2011)
Pathobiology of human-pathogenic fungi
Int J Med Microbiol 301(5):367

Hoffmann C, Ohlsen K, Hauck CR (2011)
Integrin-mediated uptake of fibronectin-binding bacteria
Eur J Cell Biol 2011 May 9 [Epub ahead of print]

Berghoff BA, Glaeser J, Sharma CM, Zobawa M, Lottspeich F, Vogel J, Klug G (2011)
Contribution of Hfq to photooxidative stress resistance and global regulation in Rhodobacter sphaeroides
Mol Microbiol 80(6):1479-95

Sharma CM, Papenfort K, Pernitzsch SR, Mollenkopf HJ, Hinton JC, Vogel J (2011)
Pervasive post-transcriptional control of genes involved in amino acid metabolism by the Hfq-dependent GcvB small RNA
Mol Microbiol 23 [Epub ahead of print]

Bergmiller T, Peña-Miller R, Boehm A, Ackermann M (2011)
Single-cell time-lapse analysis of depletion of the universally conserved essential protein YgjD
BMC Microbiol 27;11:118

Schubert S, Popp C, Rogers PD, Morschhäuser J (2011)
Functional dissection of a Candida albicans zinc cluster transcription factor, the multidrug resistance regulator Mrr1
Eukaryot Cell 10(8):1110-2

Morschhäuser J (2011)
Nitrogen regulation of morphogenesis and protease secretion in Candida albicans
Int J Med Microbiol 301(5):390-4

Khanna N, Stuehler C, Conrad B, Lurati S, Krappmann S, Einsele H, Berges C, Topp MS (2011)
Generation of a multiple pathogen-specfic T-cell product for adoptive immunotherapy based on activation-dependent expression of CD154
Blood  3 [Epub ahead of print]

Hasenberg M, Behnsen J, Krappmann S, Brakhage A, Gunzer M (2011)
Phagocyte responses towards Aspergillus fumigatus
Int J Med Microbiol 301(5):436-44

Hartmann T, Sasse C, Schedler A, Hasenberg M, Gunzer M, Krappmann S (2011)
Shaping the fungal adaptome - Stress responses of Aspergillus fumigatus
Int J Med Microbiol 301(5):408-16

Schulte LN, Eulalio A, Mollenkopf HJ, Reinhardt R, Vogel J (2011)
Analysis of the host microRNA response to Salmonella uncovers the control of major cytokines by the let-7 family
EMBO J  5 [Epub ahead of print]

Deltcheva E, Chylinski K, Sharma CM, Gonzales K, Chao Y, Pirzada ZA, Eckert MR, Vogel J, Charpentier E (2011)
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
Nature 31;471(7340):602-7

Eulalio A, Fröhlich KS, Mano M, Giacca M, Vogel J (2011)
A candidate approach implicates the secreted Salmonella effector protein SpvB in P-body disassembly
PLoS One 1;6(3):e17296

Vockenhuber MP, Sharma CM, Statt MG, Schmidt D, Xu Z, Dietrich S, Liesegang H, Mathews DH, Suess B (2011)
Deep sequencing-based identification of small non-coding RNAs in Streptomyces coelicolor
RNA Biol 1;8(3)

Sharma CM, Storz G (2011)
Interesting twists on small RNA themes in Pseudomonas aeruginosa
Mol Microbiol 11 [Epub ahead of print]

Kusch K, Hanke K, Holtfreter S, Schmudde M, Kohler C, Erck C, Wehland J, Hecker M, Ohlsen K, Bröker B, Engelmann S (2011)
The influence of SaeRS and σ(B) on the expression of superantigens in different staphylococcus aureus isolates
Int J Med Microbiol 301(6):488-99

Hertlein T, Sturm V, Kircher S, Basse-Lüsebrink T, Haddad D, Ohlsen K, Jakob P (2011)
Visualization of Abscess Formation in a Murine Thigh Infection Model of Staphylococcus aureus by F-Magnetic Resonance Imaging (MRI)
PLoS One 24;6(3):e18246

Cecil A, Rikanović C, Ohlsen K, Liang C, Bernhardt J, Oelschlaeger TA, Gulder T, Bringmann G, Holzgrabe U, Unger M, Dandekar T (2011)
 Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureus, Staphylococcus epidermidis and human cells
Genome Biol 21;12(3):R24

Schierack P, Kleta S, Tedin K, Babila JT, Oswald S, Oelschlaeger TA, Hiemann R, Paetzold S, Wieler LH (2011)
E. coli Nissle 1917 Affects Salmonella adhesion to porcine intestinal epithelial cells
PLoS One 17;6(2):e14712

Schubert S, Barker KS, Znaidi S, Schneider S, Dierolf F, Dunkel N, Aïd M, Boucher G, Rogers PD, Raymond M, Morschhäuser J (2011)
Regulation of efflux pump expression and drug resistance by the transcription factors Mrr1, Upc2, and Cap1 in Candida albicans
Antimicrob Agents 55(5):2212-23

Rennemeier C, Schwab M, Lermann U, Albert C, Kämmerer U, Frambach T, Morschhäuser J, Dietl J, Staib P (2011)
Seminal plasma protects human spermatozoa and pathogenic yeasts from capture by dendritic cells
Hum Reprod 26(5):987-99

Mogavero S, Tavanti A, Senesi S, Rogers PD, Morschhäuser J (2011)
Differential requirement of the transcription factor Mcm1 for activation of the Candida albicans multidrug efflux pump MDR1 by its regulators Mrr1 and Cap1
Antimicrob Agents Chemother 55(5):2061-6

Stuehler C, Khanna N, Bozza S, Zelante T, Moretti S, Kruhm M, Lurati S, Conrad B, Worschech E, Stevanovic S, Krappmann S, Einsele H, Latgé JP, Loeffler J, Romani L, Topp MS (2011)
Cross-protective TH1 immunity against Aspergillus fumigatus and Candida albicans
Blood  2;117(22):5881-91

Sologub L, Kuehn A, Kern S, Przyborski J, Schillig R, Pradel G (2011)
Malaria proteases mediate inside-out egress of gametocytes from red blood cells following parasite transmission to the mosquito
Cell Microbiol 13(6):897-912

Mitschke J, Georg J, Scholz I, Sharma CM, Dienst D, Bantscheff J, Voß B, Steglich C, Wilde A, Vogel J, Hess WR (2011)
An experimentally anchored map of transcriptional start sites in the model cyanobacterium Synechocystis sp. PCC6803
Proc Natl Acad Sci USA  1;108(5):2124-2129

Papenfort K, Vogel J (2011)
Sweet Business: Spot42 RNA Networks with CRP to Modulate Catabolite Repression
Mol Cell 4;41(3):245-6

Lorenz U, Lorenz B, Schmitter T, Streker K, Erck C, Wehland J, Nickel J, Zimmermann B, Ohlsen K (2011)
Functional antibodies targeting IsaA of Staphylococcus aureus augment host immune response and open new perspectives for antibacterial therapy
Antimicrob Agents Chemother 55(1):165-73

Lorenz U, Schäfer T, Ohlsen K, Tiurbe GC, Bühler C, Germer CT, Kellersmann R (2011)
In vivo detection of Staphylococcus aureus in biofilm on vascular prostheses using non-invasive biophotonic imaging
Eur J Vasc Endovasc Surg 41(1):68-75

Menzel TM, Tischer M, François P, Nickel J, Schrenzel J, Bruhn H, Albrecht A, Lehmann L, Holzgrabe U, Ohlsen K (2011)
Mode-of-action studies of the novel bisquaternary bisnaphthalimide MT02 against Staphylococcus aureus
Antimicrob Agents Chemother 55(1):311-20

Neuhäuser B, Dunkel N, Satheesh SV, Morschhäuser J (2011)
The role of the Npr1 kinase in ammonium transport and signaling by the ammonium permease Mep2 in Candida albicans
Eukaryot Cell 10(3):332-4

Morton CO, Varga JJ, Hornbach A, Mezger M, Sennefelder H, Kneitz S, Kurzai O, Krappmann S, Einsele H, Nierman WC, Rogers TR, Loeffler J (2011)
The temporal dynamics of differential gene expression in Aspergillus fumigatus interacting with human immature dendritic cells in vitro
PLoS One 14;6(1):e16016

Agarwal S, Kern S, Halbert J, Przyborski JM, Baumeister S, Dandekar T, Doerig C, Pradel G (2011)
Two nucleus-localized CDK-like kinases with crucial roles for malaria parasite erythrocytic replication are involved in phosphorylation of splicing factor
J Cell Biochem 112(5):1295-310

Coppi A, Natarajan R, Pradel G, Bennett BL, James ER, Roggero MA, Corradin G, Persson C, Tewari R, Sinnis P (2011)
The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host
J Exp Med 14;208(2):341-56

Aminake MN, Schoof S, Sologub L, Leubner M, Kirschner M, Arndt HD, Pradel G (2011)
Thiostrepton derivatives exhibit antimalarial and gametocytocidal activity by dually targeting parasite proteasome and apicoplast
Antimicrob Agents Chemother 55(4):1338-48

Dunkel N, Morschhäuser J (2011)
Loss of heterozygosity at an unlinked genomic locus is responsible for the phenotype of a Candida albicans sap4{Delta} sap5{Delta} sap6{Delta} mutant
Eukaryot Cell 10(1):54-62

2010

Podkaminski D, Vogel J (2010)
Small RNAs promote mRNA stability to activate the synthesis of virulence factors
Mol Microbiol 78(6):1327-31

Papenfort K, Bouvier M, Mika F, Sharma CM, Vogel J (2010)
Evidence for an autonomous 5' target recognition domain in an Hfq-associated small RNA
Proc Natl Acad Sci USA 23;107(47):20435-40

Borries A, Vogel J, Sharma CM (2010)
Differential RNA sequencing (dRNA-seq): Deep-sequencing based analysis of primary transcriptomes
In: Tag-based Approaches for Next-Generation Sequencing, Eds. M. Harbers, G. Kahl, Wiley-Blackwell-VCH

Büchold C, Hemberger Y, Heindl C, Welker A, Degel B, Pfeuffer T, Staib P, Schneider S, Rosenthal PJ, Gut J, Morschhäuser J, Bringmann G, Schirmeister T (2010)
New cis-Configured Aziridine-2-carboxylates as Aspartic Acid Protease Inhibitors
ChemMedChem 3;6(1):141-52

Kur K, Gabriel I, Morschhäuser J, Barchiesi F, Spreghini E, Milewski S (2010)
Disruption of homocitratesynthase genes in Candida albicansaffects growth but not virulence
Mycopathologie 170(6):397-402

Bringmann G, Hertlein-Amslinger B, Kajahn I, Dreyer M, Brun R, Moll H, Stich A, Ioset KN, Schmitz W, Ngoc LH (2010)
Phenolic analogs of the N,C-coupled naphthylisoquinoline alkaloid ancistrocladinium A, from Ancistrocladuscochinchinensis (Ancistrocladaceae), with improved antiprotozoal activities
Phytochemistry 72(1):89-93

Ghosh, S, Debnath S, Hazra S, Hartung A, Thomale K, Schultheis M, Kapkova P, Schurigt U, Moll, H, Holzgrabe U, Hazra B (2010)
Valeriana wallichii root extracts and fractions with activity against Leishmania spp.
Parasitol Res 108(4):861-71

Hoffmann C, Berking A, Agerer F, Buntru A, Neske F, Chhatwal GS, Ohlsen K, Hauck CR (2010)
Caveolin limits membrane microdomain mobility and integrin-mediated uptake of fibronectin-binding pathogens
J Cell Sci 15;123(Pt 24):4280-91

Rupp I, Sologub L, Williamson KC, Scheuermayer M, Reininger L, Doerig C, Eksi S, Kombila DU, Frank M, Pradel G (2010)
Malaria parasites form filamentous cell-to-cell connections during reproduction in the mosquito midgut
Cell Res 21(4):683-96

Navarathna DH, Das A, Morschhäuser J, Nickerson KW, Roberts DD (2010)
Dur3 is the major urea transporter in Candida albicans and is co-regulated with the urea amidolyase Dur1,2
Microbiology 157(Pt 1):270-9

Bringmann G, Bischof SK, Müller S, Gulder T, Winter C, Stich A, Moll H, Kaiser M, Brun R, Dreher J, Baumann K  (2010)
QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids
Eur J Med Chem 45(11):5370-83

Correia A, Lermann U, Teixeira L, Cerca F, Botelho S, da Costa RM, Sampaio P, Gärtner F, Morschhäuser J, Vilanova M, Pais C (2010)
Limited role of secreted aspartyl proteinases Sap1 to Sap6 in Candida albicans virulence and host immune response in murine hematogenously disseminated candidiasis
Infect Immun 78(11):4839-49

Schnitzer, J K, S. Berzel, M. Fajardo-Moser, K. A. Remer and H. Moll (2010)
Fragments of antigen-loaded dendritic cells (DC) and DC-derived exosomes induce protective immunity against Leishmania major
Vaccine 16;28(36):5785-93

Remer KA, Roeger B, Hambrecht C, Moll H (2010)
Natural killer cells support the induction of protective immunity during dendritic cell-mediated vaccination against Leishmania major
Immunology 131(4):570-82

Schurigt, U, Schad C, Glowa C, Baum U, Thomale K, Schnitzer JK, Schultheis M, Schaschke N, Schirmeister T, Moll H (2010)
Aziridine-2,3-dicarboxylate-based cysteine cathepsin inhibitors induce cell death in Leishmania major associated with accumulation of debris in autophagy-related lysosome-like vacuoles
Antimicrob Agents Chemother 54(12):5028-41

Papenfort K, Vogel J  (2010)
Regulatory RNA in bacterial pathogens
Cell Host Microbe 22;8(1):116-27

Hartmann T, Dümig M, Jaber BM, Szewczyk E, Olbermann P, Morschhäuser J, Krappmann S (2010)
Validation of a self-excising marker in the human pathogen Aspergillusfumigatus by employing the beta-rec/six site-specific recombination system
Appl Environ Microbiol 76(18):6313-7

Hartmann T, Dümig M, Jaber BM, Szewczyk E, Olbermann P, Morschhäuser J, Krappmann S  (2010)
Validation of a self-excising marker in the human pathogen Aspergillusfumigatus by employing the beta-rec/six site-specific recombination system
Appl Environ Microbiol 76(18):6313-7

Dobrindt U, Hacker J (2010)
Nosocomial infections and their control
Int J Med Microbiol 300(6):341

Liebeke M, Meyer H, Donat S, Ohlsen K, Lalk M (2010)
A metabolomic view of Staphylococcus aureus and its ser/thr kinase and phosphatase deletion mutants: involvement in cell wall biosynthesis
ChemBiol 27;17(8):820-30

Sibbald MJ, Winter T, van der Kooi-Pol MM, Buist G, Tsompanidou E, Bosma T, Schäfer T, Ohlsen K, Hecker M, Antelmann H, Engelmann S, van Dijl JM (2010)
Synthetic effects of secG and secY2 mutations on exoproteome biogenesis in Staphylococcus aureus
J Bacteriol 192(14):3788-800

Papenfort K, Vogel J (2010)
Regulatory RNA in bacterial pathogens
Cell Host Microbe 22;8(1):116-27

Sibbald MJ, Winter T, van der Kooi-Pol MM, Buist G, Tsompanidou E, Bosma T, Schäfer T, Ohlsen K, Hecker M, Antelmann H, Engelmann S, van Dijl JM (2010)
Synthetic effects of secG and secY2 mutations on exoproteome biogenesis in Staphylococcus aureus
J Bacteriol 192(14):3788-800

Gronbach K, Eberle U, Müller M, Ölschläger TA, Dobrindt U, Leithäuser F, Niess JH, Döring G, Reimann J, Autenrieth IB, Frick JS (2010)
Safety of probiotic Escherichia coli strain Nissle 1917 depends on intestinal microbiota and adaptive immunity of the host
Infect Immun 78(7):3036-46

Purcell LA, Leitao R, Ono T, Yanow SK, Pradel G, Spithill TW, Rodriguez A (2010)
A putative kinase-related protein (PKRP) from Plasmodium berghei mediates infection in the midgut and salivary glands of the mosquito
Int J Parasitol 40(8):979-88

Javayel S, Papenfort K, Vogel J (2010)
The small RNAs of Salmonella
Salmonella Molecular & Cellular Miology (Edited by S. Prowollik), Horizon Press, 2010, in press

Irnov I, Sharma CM, Vogel J, Winkler WC (2010)
Identification of regulatory RNAs in Bacillus subtilis
Nucleic Acids Res 1;38(19):6637-51

Herbert S, Ziebandt AK, Ohlsen K, Schäfer T, Hecker M, Albrecht D, Novick R, Götz F (2010)
Repair of global regulators in Staphylococcus aureus 8325 and comparative analysis with other clinical isolates
Infect Immun 78(6):2877-89

Lehti TA, Bauchart P, Heikkinen J, Hacker J, Korhonen TK, Dobrindt U, Westerlund-Wikström B (2010)
The Mat fimbria promotes biofilm formation by meningitis-associated Escherichia coli
Microbiology 156(Pt 8):2408-17

Bohn C, Rigoulay C, Chabelskaya S, Sharma CM, Marchais A, Skorski P, Borezée-Durant E, Barbet R, Jacquet E, Jacq A, Gautheret D, Felden B, Vogel J, Bouloc P (2010)
Experimental discovery of small RNAs in Staphylococcus aureus reveals a riboregulator of central metabolism
Nucleic Acids Res 1;38(19):6620-36

Bauchart P, Germon P, Brée A, Oswald E, Hacker J, Dobrindt U (2010)
Pathogenomic comparison of human extraintestinal and avian pathogenic Escherichia coli--search for factors involved in host specificity or zoonotic potential
MicrobPathog 49(3):105-15

Dobrindt U, Zdziarski J, Salvador E, Hacker J (2010)
Bacterial genome plasticity and its impact on adaptation during persistent infection
Int J Med Microbiol 300(6):363-6

Dobrindt U, Chowdary MG, Krumbholz G, Hacker J (2010)
Genome dynamics and its impact on evolution of Escherichia coli
Med MicrobiolImmunol 199(3):145-54

Moriel DG, Bertoldi I, Spagnuolo A, Marchi S, Rosini R, Nesta B, Pastorello I, Corea VA, Torricelli G, Cartocci E, Savino S, Scarselli M, Dobrindt U, Hacker J, Tettelin H, Tallon LJ, Sullivan S, Wieler LH, Ewers C, Pickard D, Dougan G, Fontana MR,Rappuoli R, Pizza M, Serino L (2010)
Identification of protective and broadly conserved vaccine antigens from the genome of extraintestinal pathogenic Escherichia coli
ProcNatlAcadSci U S A 18;107(20):9072-7

Hennig S, Ziebuhr W (2010)
Characterization of the Transposase Encoded by IS256, the Prototype of a Major Family of Bacterial Insertion Sequence Elements
J Bacteriol 192(16):4153-63

Kur K, Gabriel I, Morschhäuser J, Barchiesi F, Spreghini E, Milewski S (2010)
Disruption of Homocitrate Synthase Genes in Candida albicansaffects growth but not virulence
Mycopathologia 170(6):397-402

Tischer M, Sologub L, Pradel* G, Holzgrabe* U (2010)
The bisnaphthalimides as new active lead compounds against Plasmodium falciparum
Bioorg Med Chem  1;18(9):2998-3003

Szewczyk E, Krappmann S (2010)
Conserved regulators of mating are essential for Aspergillusfumigatuscleistothecium formation
Eukaryot Cell  9(5):774-83

Mitra BN, Pradel G, Frevert U, Eichinger D  (2010)
Compounds of the upper gastrointestinal tract induce rapid and efficient excystation of Entamoebainvadens
Int J Parasitol 40(6):751-60

Kuehn A, Pradel G (2010)
The coming-out of malaria gametocytes
J Biomed Biotechnol  976827

Dobrindt U (2010)
Virulence factors of uropathogens
Urologe A 49(5):598-605

Ohlsen K, Lorenz U (2010)
Immunotherapeutic strategies to combat staphylococcal infections
Int J Med Microbiol 300(6):402-10

Geiger T, Goerke C, Fritz M, Schäfer T, Ohlsen K, Liebeke M, Lalk M, Wolz C  (2010)
Role of the (p)ppGpp synthase RSH, a RelA/SpoT homolog, in stringent response and virulence of Staphylococcus aureus
Infect Immun 78(5):1873-83

Stritzker J, Weibel S, Seuber C, Götz A, Tresch A, van Rooijen N, Oelschlaeger TA, Hill PJ, Gentschev I, Szalay AA (2010)
Enterobacterial tumor colonization in mice depends on bacterial metabolism and macrophages but is independent of chemotaxis and motility
Int J Med Microbiol 300(7):449-56

Oelschlaeger TA (2010)
Mechanisms of probiotic actions – a review
Int J Med Microbiol 300(1):57-62

Weisser M, Schoenfelder SM, Orasch C, Arber C, Gratwohl A, Frei R, Eckart M, Fluckiger U,
Ziebuhr W (2010)
Hypervariability of biofilm formation and oxacillin resistance in a Staphylococcus epidermidis
strain causing persistent severe infection in an immunocompromised patient
J ClinMicrobiol 48(7):2407-12

Schoenfelder SM, Lange C, Eckart M, Hennig S, Kozytska S, Ziebuhr W (2010)
Success through diversity - How Staphylococcus epidermidis establishes as a nosocomial pathogen
Int J Med Microbiol 300(6):380-6

Morschhäuser J (2010)
Regulation of white-opaque switching in Candida albicans
Med MicrobiolImmunol 199(3):165-72

Kuehn A, Simon N, Pradel G (2010)
Family members stick together: multi-protein complexes of malaria parasites
Med MicrobiolImmunol 199(3):209-26

Schoof S, Pradel* G, Aminake MN, Ellinger B, Baumann S, Potowski M, Najajreh Y, Kirschner M, Arndt* HD (2010)
Antiplasmodialthiostrepton derivatives: proteasome inhibitors with a dual mode of action
AngewChemInt Ed Engl 26;49(19):3317-21

Pradel G, Schlitzer M (2010)
Antibiotics in malaria therapy and their effect on the parasite apicoplast
CurrMol Med 10(3):335-49

Jelsbak L, Hemmingsen L, Donat S, Ohlsen K, Boye K, Westh H, Ingmer H, Frees D  (2010)
Growth phase-dependent regulation of the global virulence regulator Rot in clinical isolates of Staphylococcus aureus
Int J Med Microbiol 300(4):229-36

Kozytska S, Stauß D, Pawlik MC, Hensen S, Eckart M, Ziebuhr W, Witte W, Ohlsen K (2010)
Identification of specific genes in Staphylococcus aureus strains associated with bovine mastitis
Vet Microbiol 26;145(3-4):360-5

Sharma CM, Hoffmann S, Darfeuille F, Reignier J, Findeiss S, Sittka A, Chabas S, Reiche K, Hackermüller J, Reinhardt R, Stadler PF, Vogel J (2010)
The primary transcriptome of the major human pathogen Helicobacter pylori
Nature 11;464(7286):250-5

Chao Y, Vogel J (2010)
The role of Hfq in bacterial pathogens
CurrOpinMicrobiol 13(1):24-33

Miller M, Donat S, Rakette S, Stehle T, Kouwen TR, Diks SH, Dreisbach A, Reilman E, Gronau K, Becher D, Peppelenbosch MP, van Dijl JM, Ohlsen K (2010)
Staphylococcal PknB as the first prokaryotic representative of the proline-directed kinases
PLoS One 4;5(2):e9057

Cuny C, Friedrich A, Kozytska S, Layer F, Nübel U, Ohlsen K, Strommenger B, Walther B, Wieler L, Witte W (2010)
Emergence of methicillin-resistant Staphylococcus aureus (MRSA) in different animal species
Int J Med Microbiol 300(2-3):109-17

Chlebowicz MA, Nganou K, Kozytska S, Arends JP, Engelmann S, Grundmann H, Ohlsen K, van Dijl JM, Buist G (2010)
Recombination between ccrC genes in a type V (5C2&5) staphylococcal cassette chromosome mec (SCCmec) of Staphylococcus aureus ST398 leads to conversion from methicillin resistance to methicillin susceptibility in vivo
Antimicrob Agents Chemother 54(2):783-91

Ohlsen K, Donat S (2010)
The impact of serine/threonine phosphorylation in Staphylococcus aureus
Int J Med Microbiol 300(2-3):137-41

Pimentel-Elardo SM, Kozytska S, Bugni TS, Ireland CM, Moll H, Hentschel U (2010)
Anti-parasitic compounds from Streptomyces sp. strains isolated from Mediterranean sponges
Mar Drugs 23;8(2):373-80

Morschhäuser J (2010)
Regulation of multidrug resistance in pathogenic fungi
Fungal Genet Biol47(2):94-106

Albrecht M, Sharma CM, Reinhardt R, Vogel J, Rudel T (2010)
Deep sequencing-based discovery of the Chlamydia trachomatis transcriptome
Nucleic Acids Res 38(3):868-77

Müller CM, Schneider G, Dobrindt U, Emödy L, Hacker J, Uhlin BE (2010)
Differential effects and interactions of endogenous and horizontally acquired H-NS-like proteins in pathogenic Escherichia coli
MolMicrobiol 75(2):280-93

Ziebandt AK, Kusch H, Degner M, Jaglitz S, Sibbald MJ, Arends JP, Chlebowicz MA, Albrecht D, Pantucek R, Doskar J, Ziebuhr W, Broker BM, Hecker M, van Dijl JM, Engelmann S (2010)
Proteomics uncovers extreme heterogeneity in the Staphylococcus aureusexoproteome due to genomic plasticity and variant gene regulation
Proteomics 10(8):1634-44

Oelschlaeger TA, Dobrindt U, Hacker J (2010)
Cell wall structure and pathogenicity, IN: Procaryotic cell wall compounds - Structure and biochemistry
(König H, Claus H, Varma A, eds.) pp.: 313-343, Springer- Verlag Berlin Heidelberg

Ponte-Sucre A, Gulder T, Gulder TAM, Vollmers G, Bringmann G, Moll H (2010)
Alterations on the structure of Leishmania major induced by N-arylisoquinolines correlate with compound accumulation and disposition
J Med Microbiol 59(Pt 1):69-75

Nowotny B, Schneider T, Pradel G, Schirmeister T, Rethwilm A, Kirschner M (2010)
Inducible APOBEC3G-Vif double stable cell line as a high-throughput screening platform to identify antiviral compounds
Antimicrob Agents Chemother 54(1):78-87

Heilmann CJ, Schneider S, Barker KS, Rogers PD, Morschhäuser J (2010)
An A643T mutation in the transcription factor Upc2p causes constitutive ERG11 upregulation and increased fluconazole resistance in Candida albicans
Antimicrob Agents Chemother 54(1):353-9